There are many comments of
radioactive particle implantation:
Non-invasive,
bloodless
Painless, low rates of side effects
Increase life expentancy and quality of life
Three-dimensional
radioactive seed implants (internal radiation system): Iodine implants are 0.8
mm in thickness, about 0.4 cm in length.
Then what
is radioactive particle implantation? Modern Cancer Hospital Guangzhou (www.asiancancer.com ) will introduce it following.
1. Treatment principle
125I
seeds implant are an energy radionuclide which can give off
continuous, short-range γ-ray to kill tumor cells. It can achieve the same
internal radiation effects on tumor as surgery does. Hence, it is called seeds
knife.
Benefits
Radiation is limited to inside tumor and
avoid damage to normal tissue. Effectively kill tumor by continuous and effective exposure up to 180 days.
Relieve pain and increase survival rate and quality of life
2. Procedures
Tumor size from CT and MR results is input into three-dimensional treatment planning system (TPS) to construct a dimensional image with the same size as that of actual tumor. The number of I seed implants, location of each implant and overall treatment plan depends on tumor location, shape and size.
Under CT or ultrasound guidance, I 125 seed implants are directly placed into the tumor by a special set of equipment or placed into residual tumor bed and possible paths of metastatic lymph node spread. These implants keep emitting γ-ray within tumor, as "land mines" targets tumor cells accurately.
3. How you feel after implantation
125I seed implantation has fewer complications and mild side effects. Thus it will not lead to severe organ dysfunctions. Therefore, most patients feel nothing special after the procedure.
4. Indication
It applies to a variety of primary and metastatic tumors.
5. the number of I seeds to implant
Bigger the tumor is, more I 125 seeds are needed implanting. Sometimes even one implantation procedure could eliminate all of the tumor. More I seeds can be implanted if an insufficient number of seeds is detected in follow-ups.
6. Duration of therapeutic effect
Effective radiation effect of 125I seeds can be present for about 180 days due to its 60.1-day half-life period and gradual attenuation of radiation dose.
7. Can radioactive seed implantation therapy prevent cancer recurrence?
Radioactive seed implantation is a local therapy for tumor coming into being and to kill cancer cell in implants site. It can effectively and thoroughly kill cancer in conjunction with other treatments , such as A -He cryotherapy.
8. How to verify therapeutic effect of I seeds implants?
125 I seed implants in human body can continuously emit γ-ray to attack cancer cells. Radiation energy accumulated to a certain extent could lead to gradual necrosis of cancer cells through continuous radiation. Therefore, radioactive implants action is a continuous and slow process until cancer cells are killed. Generally speaking, necrosis of cancer cells is remarkable in 2 to 3 months after I seeds implantation. The resulted shrinkage of tumor is visible for body surface tumor whereas resulted shrinkage or necrosis has to be presented by CT or ultrasound.
9. Cautions
Effective range of 125 I seeds implants is 1.7cm. There is no concern about radiation safety because radiation damage to doctors and patients is far lower than national protection standards.
Patients with seeds implants should not have close contact with pregnant women or children under three years old within the first 2 months after the procedure. Two months later, patients can return to normal life as the radiation fades.
Outer shell of radioactive seed implants is made of titanium which is not subjected to magnetic fields action. Patients are allowed to take CT, MRI,X ray and ultrasound after radioactive seed implantation.
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